When young males reach puberty, the levels of testosterone that their body produces skyrockets. Testosterone is responsible for many common male characteristics, including a deep voice, body hair, muscle strength, and even aggression. It is also responsible for sexual drive.
By the time a male reaches the age of 18, his testosterone levels have peaked. They will remain high until he turns 24 or 25, at which point they will begin to decline steadily over the next several years. Through his 30s and into his 40s, testosterone levels will continue to decline and this can lead to a variety of problems, including a loss of energy, strength, difficulty keeping off excess weight, lower libido, and other issues.
L-DOPA is one of the many testosterone boosting supplements that are marketed to have a direct impact on inspiring the body to produce more testosterone.
L-DOPA is also common really referred to as levodopa and is commonly used in conduction in conjunction with carbidopa. They are used to treat Parkinson’s disease as well as other Parkinson’s -like symptoms, including stiffness, difficulty moving, and shakiness.
Levodopa will change into dopamine in the brain which can help control movement. Carbidopa helps to prevent the breakdown of levodopa in the bloodstream. There are numerous other potential benefits that this supplement may provide, and whether it has a direct impact on testosterone levels in the body is difficult to ascertain from the research studies that we have culled from around the world.
We have included three of the research studies that tested L-DOPA on various subjects.
In 1987, Prelevic, Wurzburger, and Peric of the Department of Endocrinology, Medical Centre “Zvezdara”, Belgrade University School of Medicine, Beograd, Yugoslavia sought to determine the effects of L-DOPA on various health related conditions of female patients. It is unclear from the research that is presented the size of the research study or the dosages that were provided to the test subjects. The researchers did not note whether or not they tested testosterone levels.
However, they did find that there was a statistically significant decrease in luteinizing hormone in the body among test subjects. LH stimulates the production of testosterone, so in this study, even though it was testing women, the researchers determined a decrease in LH, which could be significant.
(Read more about this study at NCBI.)
In 1972, researchers Boden, Lundy, and Owen sought to determine the effect that L-DOPA would have on anterior pituitary hormones in male subjects. They chose six control and nine test subjects for this research study.
They administered 500 mg of levodopa to the test subjects. They found that LH levels decreased by a small quantity in seven of the nine test subjects.
(Read more about this study at Karger.)
Finally, in 1995, Yamada, Nakamura, et al. at the Environmental Health Science Laboratory, Sumitomo Chemical Co., Ltd., Osaka, Japan tested L-DOPA on laboratory rats to determine its impact on serum luteinizing hormone levels.
The researchers found that serum testosterone levels among the tested rats tended to be higher among those that were given the treatment as opposed to the placebo group.
These researchers found that LH levels increased significantly within four hours after a single administration of the treatment dosage. That treatment dosage was 1000 mg per kilogram body weight. They did not notice any increase in LH levels when testing at 20 mg, 100 mg, or 200 mg per kilogram body weight.
The researchers determined that a prolonged treatment of L-DOPA induces the release of LH from the pituitary gland, which has a direct impact on elevating LH levels in peripheral circulation. This could have a direct and positive impact on overall total testosterone levels in the body.
(Read more about this study at NCBI.)
While the research on L-DOPA is relatively sparse, and considering that two of the studies are nearly two to three decades old, the most recent research study that directly connected any potential impact that L-DOPA could have on testosterone levels found that, at least in laboratory rats, prolonged treatment using L-DOPA can actually increase levels of luteinizing hormone.
Because an increase in luteinizing hormone can have a direct impact on boosting testosterone levels, it can be stated that L-DOPA may be effective as a testosterone boosting supplement.
We will continue to seek out other research studies that have directly tested the impact of L-DOPA on testosterone levels in the body of human male subjects. We will post those studies if and as they are published.